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Structural and mechanistic insights into the bacterial amyloid …

2014年9月14日After secretion, CsgB nucleates CsgA subunits into curli fibres7,11,12. Secretion and extracellular deposition of CsgA and CsgB are dependent on two soluble accessory factors, respectively CsgE ...

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2014年9月14日Each CsgG monomer is composed of four β-strands that span the outer membrane. Nine CsgG monomers together form a large, 36-stranded β-barrel with a central secretion channel.###2020年6月19日Two outer membrane proteins, CsgG and CsgF, form the core apparatus for secretion and assembly of the curli structural subunits.

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A dual-constriction biological nanopore resolves ... - Nature

2020年7月6日We now combine the CsgG nanopore with the 35-residue N-terminal region of its extracellular interaction partner CsgF to produce a dual-constriction pore with improved signal and base-calling ...

Nanopore DNA sequencing technologies and their …

2024年3月6日The readout signals using the CsgG–CsgF pore are more complex than the single-reading-head CsgG, so adapted algorithms for signal deciphering are used 78.

Structure of the nonameric bacterial amyloid secretion channel

2014年12月1日Here, we report the crystal structure of CsgG, a lipoprotein that forms a secretion channel for curli subunits in the outer membrane. Each CsgG monomer is composed of four β-strands that span the outer membrane. Nine CsgG monomers together form a large, 36-stranded β-barrel with a central secretion channel.

Cryo-EM structure of the nonameric CsgG-CsgF complex and …

2020年6月19日Two outer membrane proteins, CsgG and CsgF, form the core apparatus for secretion and assembly of the curli structural subunits. The cryo-EM structure of the CsgG-CsgF complex reveals a unique amyloid secretion channel with two tandem constriction regions.

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